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HYPURITY C18 5UM 150X4.6MM COLUMNS

The Thermo Scientific™ HyPURITY™ C18 HPLC Column (5 µm, 150 × 4.6 mm) is a premium reversed-phase analytical HPLC column engineered for high-resolution separations, exceptional reproducibility, and long column life. Built on highly characterized, ultra-pure silica with an endcapped C18 stationary phase, the HyPURITY™ C18 column delivers outstanding peak symmetry, excellent efficiency, and consistent chromatographic performance across a broad range of analytical applications.

Designed for pharmaceutical, environmental, food, chemical, biotechnology, and research laboratories, the HyPURITY™ C18 column provides reliable separation of acidic, basic, and neutral compounds. Its 190 Å pore size, 13% carbon loading, and 200 m²/g surface area offer excellent retention characteristics while supporting high sample loading and reproducible results.

SKU: 22105-154631 Category: Brand:

Specifications

Parameter Specification
Product Type Analytical HPLC Column
Brand Thermo Scientific™
Product Series HyPURITY™
Chromatography Type Reversed Phase (RP-HPLC)
Stationary Phase C18
USP Classification L1
Column Dimensions 150 × 4.6 mm
Particle Size 5 µm
Pore Size 190 Å
Surface Area 200 m²/g
Carbon Load 13%
Packing Material High-Purity Silica
Endcapped Yes
pH Range 1–9
For Use With HPLC & LC/MS Systems

Features

  • Premium reversed-phase analytical HPLC column
  • Thermo Scientific™ HyPURITY™ C18 stationary phase
  • Column dimensions: 150 × 4.6 mm
  • Particle size: 5 µm
  • High-purity silica packing material
  • Endcapped C18 bonded phase
  • USP L1 column classification
  • Surface area: 200 m²/g
  • Pore size: 190 Å
  • Carbon loading: 13%
  • Operating pH range: 1–9
  • Excellent peak symmetry and reproducibility
  • High column efficiency with low bleed
  • Suitable for LC/MS applications
  • Consistent batch-to-batch performance
  • Excellent retention for acidic, basic, and neutral compounds
  • Designed for routine analytical and research applications

Benefits

  • Excellent Chromatographic Performance: Provides high separation efficiency, sharp peak shapes, and excellent reproducibility for demanding analytical methods.
  • Superior Batch-to-Batch Consistency: Every batch of silica and bonded phase is extensively characterized and validated, ensuring reliable chromatographic performance.
  • Wide pH Compatibility: Stable across a pH range of 1–9, allowing greater flexibility in mobile phase selection.
  • Optimized for Routine HPLC Analysis: The 5 µm particle size delivers an ideal balance between separation efficiency and operating pressure.
  • High Sample Loading Capacity: The 190 Å pore size and 200 m²/g surface area provide efficient analyte interaction and improved chromatographic performance.
  • Excellent Peak Symmetry: Endcapped C18 chemistry minimizes secondary interactions for improved resolution and quantitation.
  • LC/MS Compatible: Low-bleed stationary phase supports sensitive LC/MS analyses.
  • Long Service Life: Durable silica support and optimized bonding chemistry provide excellent column longevity under routine laboratory conditions.

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