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Hypersil GOLD™ C8 , 150 X 2.1, 1.9u HPLC Columns

The Thermo Scientific™ Hypersil GOLD™ C8 HPLC Column (150 × 2.1 mm, 1.9 µm) is a premium UHPLC/HPLC reversed-phase analytical column designed to deliver exceptional chromatographic performance for compounds with medium hydrophobicity. Featuring an advanced Hypersil GOLD™ C8 stationary phase based on ultrapure silica, the column provides excellent peak symmetry, high efficiency, improved sensitivity, and reproducible separations for pharmaceutical, environmental, food, clinical, and research laboratories.

Manufactured using fully porous spherical silica particles (1.9 µm) with an 8% carbon load, the column offers fast analysis, superior resolution, and excellent retention characteristics while reducing hydrophobic interactions compared to traditional C18 columns. This makes it an ideal choice for analytes requiring shorter retention times and optimized selectivity.

SKU: 25202-152130 Category: Brand:

Specifications

Parameter Specification
Product Type Analytical HPLC/UHPLC Column
Brand Thermo Scientific™
Product Series Hypersil GOLD™
Stationary Phase C8
Chromatography Type Reversed Phase
Column Dimensions 150 × 2.1 mm
Particle Size 1.9 µm
Particle Type Fully Porous
Packing Material Spherical Ultrapure Silica
USP Classification L7
Carbon Load 8%
Pore Size 175 Å
Surface Area 220 m²/g
pH Range 2–9
Maximum Pressure 1250 bar (18,130 psi)
Maximum Temperature 60°C
Endcapped Yes
Recommended Use UHPLC & High-Performance HPLC

Features

  • Thermo Scientific™ Hypersil GOLD™ C8 analytical HPLC/UHPLC column
  • Column dimensions: 150 × 2.1 mm
  • Particle size: 1.9 µm
  • Reversed-phase C8 stationary phase
  • Fully porous spherical ultrapure silica particles
  • USP L7 packing material
  • 8% carbon load for optimized selectivity
  • 175 Å pore size
  • Surface area of 220 m²/g
  • Excellent peak symmetry and narrow peak widths
  • High chromatographic efficiency and sensitivity
  • Enhanced resolution for complex sample analysis
  • Reduced hydrophobic retention compared to C18 columns
  • Wide pH operating range (2–9)
  • Maximum operating pressure: 1250 bar (18,130 psi)
  • Maximum operating temperature: 60°C
  • Excellent batch-to-batch reproducibility
  • Suitable for UHPLC and high-performance HPLC applications

Benefits

  • Outstanding Peak Shape: Advanced Hypersil GOLD™ chemistry delivers highly symmetrical peaks, improving quantification accuracy and analytical reliability.
  • Optimized Retention for Medium Hydrophobic Compounds: The C8 stationary phase provides lower hydrophobic retention than C18, making it suitable for compounds requiring faster elution.
  • Superior Separation Efficiency: The 1.9 µm fully porous particles provide high column efficiency, narrow peaks, and excellent chromatographic resolution.
  • Improved Sensitivity: Sharp peak profiles enhance detection sensitivity, particularly for trace-level analytes.
  • Reliable Reproducibility: High manufacturing consistency ensures dependable column-to-column performance for validated analytical methods.
  • Fast UHPLC Analysis: Designed for high-pressure UHPLC systems, enabling shorter run times while maintaining excellent separation quality.
  • Broad Chemical Compatibility: The pH range of 2–9 allows flexibility across a wide variety of mobile phases and analytical methods.
  • Suitable for Method Development: An excellent choice when C18 columns provide excessive retention or when improved selectivity is required.

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