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Hypersil Silica, 250 x 4.6 mm, 5µm

The Thermo Scientific™ Hypersil™ Silica HPLC Column (250 × 4.6 mm, 5 µm) is a high-performance normal-phase HPLC analytical column designed for the separation of non-polar and moderately polar compounds in pharmaceutical, chemical, food, environmental, and research laboratories. Manufactured using high-purity spherical silica particles, the column delivers excellent chromatographic efficiency, reproducibility, and long service life for routine analytical applications.

Recognized as an industry-standard HPLC column, the Hypersil™ Silica stationary phase offers consistent batch-to-batch reproducibility, narrow particle size distribution, and excellent column efficiency. The 250 mm length provides enhanced separation capability for complex mixtures, while the 5 µm particle size ensures an ideal balance between efficiency and operating pressure.

SKU: 30005-254631 Category: Brand:

Specifications

Parameter Specification
Product Type Normal-Phase HPLC Column
Brand Thermo Scientific™
Product Line Hypersil™
Stationary Phase Silica
Column Dimensions 250 × 4.6 mm
Particle Size 5 µm
Column Format Analytical Column
Packing Material High-Purity Spherical Silica
Particle Type Fully Porous
USP Classification L3
Pore Size 120 Å
Surface Area 170 m²/g
Maximum Pressure 400 bar (5800 psi)
Operating pH Range 2–8
Maximum Temperature 60°C
Chromatography Mode Normal Phase HPLC

Features

  • High-performance normal-phase HPLC analytical column
  • Thermo Scientific™ Hypersil™ Silica stationary phase
  • Column dimensions: 250 × 4.6 mm
  • 5 µm spherical silica particles
  • High-purity silica packing material
  • Narrow particle size distribution
  • Excellent chromatographic efficiency
  • Outstanding batch-to-batch reproducibility
  • Long operational column lifetime
  • High separation performance
  • Maximum operating pressure: 400 bar (5800 psi)
  • Operating pH range: 2–8
  • Pore size: 120 Å
  • Surface area: 170 m²/g
  • Suitable for normal-phase HPLC applications
  • USP Classification: L3
  • Compatible with standard HPLC systems

Benefits

  • Excellent Separation Performance: High-purity silica stationary phase provides efficient separation of non-polar and moderately polar compounds.
  • Reliable Analytical Results: Excellent batch-to-batch reproducibility ensures consistent chromatographic performance across analyses.
  • High Column Efficiency: Uniform spherical silica particles produce sharp peaks, improved resolution, and reliable retention.
  • Long Service Life: Durable packing material and high-quality manufacturing help maximize column lifetime under recommended operating conditions.
  • Optimized for Routine Analysis: The 250 mm column length provides excellent resolution for complex sample separations.
  • Wide Application Compatibility: Suitable for pharmaceutical, food, environmental, chemical, and research laboratories.
  • Stable Operating Conditions: Supports operation from pH 2–8 with pressure resistance up to 400 bar.
  • Improved Laboratory Productivity: Delivers dependable performance for routine quality control, method development, and research applications.

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