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ACCLAIM 120 C18 2.2UM2.1X100MM

The Thermo Scientific™ Acclaim™ 120 C18 HPLC Column (2.2 µm, 2.1 × 100 mm) is a high-performance reversed-phase analytical HPLC column designed to deliver exceptional resolution, reproducibility, and sensitivity for demanding chromatographic separations. Built using ultrapure spherical silica with advanced C18 bonding and end-capping technology, the column provides excellent peak symmetry, minimal secondary interactions, and outstanding reproducibility for pharmaceutical, biopharmaceutical, environmental, food, and research laboratories.

The 2.2 µm particle size enables high-efficiency separations while maintaining compatibility with UHPLC and RSLC systems. With a 120 Å pore size, 18% carbon loading, and 300 m²/g surface area, the Acclaim™ 120 C18 column offers excellent retention and separation of a broad range of small molecules and organic compounds.

SKU: 68982 Category: Brand:

Specifications

Parameter Specification
Product Type Reversed-Phase HPLC Column
Brand Thermo Scientific™
Product Line Acclaim™ 120 C18
Column Dimensions 2.1 × 100 mm
Particle Size 2.2 µm
Column Format Analytical Column
Stationary Phase C18
Packing Material Spherical, Fully Porous Ultrapure Silica
End-Capped Yes
USP Classification L1
Pore Size 120 Å
Carbon Load 18%
Surface Area 300 m²/g
Column Type Reversed Phase
pH Stability 2–8
Maximum Operating Pressure 800 bar (11,600 psi)
Maximum Temperature 60°C
LC-MS Compatible Yes
Quantity 1 Column

Features

  • High-performance reversed-phase analytical HPLC column
  • Thermo Scientific™ Acclaim™ 120 C18 series
  • Column dimensions: 2.1 × 100 mm
  • Particle size: 2.2 µm
  • Stationary phase: C18 (L1)
  • Fully end-capped bonded silica
  • Ultrapure spherical fully porous silica packing
  • 120 Å pore size
  • 18% carbon loading
  • Surface area: 300 m²/g
  • Excellent peak symmetry and high efficiency
  • Very low metal content minimizes peak tailing
  • Extremely low column bleed for LC-MS compatibility
  • Stable operating pH range: 2–8
  • Maximum operating pressure: 800 bar (11,600 psi)
  • Suitable for HPLC, UHPLC, RSLC, and LC-MS applications
  • Excellent batch-to-batch reproducibility
  • Designed for high-resolution analytical separations

Benefits

  • Exceptional Separation Efficiency: The 2.2 µm particle technology delivers high-resolution separations with improved peak capacity and faster analysis.
  • Excellent Peak Shape: Advanced C18 bonding and ultra-low metal content minimize secondary interactions and reduce peak tailing.
  • Reliable Reproducibility: Manufactured under strict quality standards to provide consistent column-to-column and batch-to-batch performance.
  • LC-MS Compatible: Extremely low column bleed improves sensitivity and reduces background noise in mass spectrometry applications.
  • Broad Analytical Compatibility: Suitable for pharmaceutical compounds, peptides, environmental contaminants, food additives, and other organic molecules.
  • High Pressure Performance: Designed to operate up to 800 bar, making it compatible with modern UHPLC and RSLC systems.
  • Extended Column Life: High-purity silica and durable bonding chemistry provide excellent chemical stability and long service life.
  • Versatile Method Development: Supports routine analytical testing, quality control, research, and method development across multiple industries.

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