The Thermo Scientific™ BioBasic™ SEC 120 5 µm 300 × 7.8 mm Preparative HPLC Column is a high-performance Size Exclusion Chromatography (SEC) column designed for the efficient separation and purification of water-soluble biomolecules based on their molecular size and shape. Engineered with a 120 Å pore size and 5 µm spherical ultrapure silica particles bonded with a diol (OH) stationary phase, this preparative column delivers high separation efficiency, excellent reproducibility, and long operational life for laboratory and preparative chromatography applications.
The BioBasic SEC 120 Preparative Column is ideal for separating proteins, peptides, enzymes, antibodies, nucleic acids, and other biomolecules across a molecular weight range of approximately 700 to 120,000 Daltons. The size exclusion mechanism minimizes secondary interactions, ensuring gentle separation while preserving the native structure and biological activity of sensitive biomolecules.