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AQUASIL C18 3UM 100X4.6MM COLUMN

The Thermo Scientific™ AQUASIL™ C18 3 µm, 100 × 4.6 mm HPLC Column is a high-performance reversed-phase analytical HPLC column designed for the separation of polar and moderately hydrophobic compounds. Featuring a polar endcapped C18 stationary phase, the column provides improved retention of polar analytes while maintaining excellent chromatographic performance under highly aqueous mobile phase conditions.

Packed with 3 µm high-purity silica particles and a 100 Å pore size, the AQUASIL™ C18 column delivers high efficiency, sharp peak shapes, and excellent reproducibility for routine analytical, pharmaceutical, environmental, food, and research laboratory applications. Its 100 mm × 4.6 mm analytical format offers an ideal balance of resolution, speed, and sensitivity for HPLC and LC/MS workflows.

SKU: 77503-104630 Category: Brand:

Specifications

Parameter Specification
Product Type Analytical HPLC Column
Brand Thermo Scientific™
Product Line AQUASIL™
Stationary Phase C18 (Polar Endcapped)
Column Type Reversed Phase
Column Dimensions 100 × 4.6 mm
Particle Size 3 µm
Pore Size 100 Å
Packing Material High-Purity Silica
Surface Area 310 m²/g
Carbon Load 12%
USP Classification L1
Endcapped Yes
pH Range 2–8
Mobile Phase Compatibility Compatible with 100% Aqueous Mobile Phases
Suitable For HPLC & LC/MS Applications

Features

  • Reversed-phase analytical HPLC column
  • Polar endcapped C18 stationary phase
  • Particle size: 3 µm
  • Column dimensions: 100 × 4.6 mm
  • High-purity silica packing material
  • 100 Å pore size
  • Compatible with 100% aqueous mobile phases
  • Improved retention of polar compounds
  • Alternative selectivity compared to conventional C18 columns
  • High chromatographic efficiency
  • Excellent peak symmetry and reproducibility
  • Suitable for HPLC and LC/MS applications
  • Wide operating pH range of 2–8
  • USP L1 column classification
  • Carbon load: 12%
  • Surface area: 310 m²/g

Benefits

  • Enhanced Polar Compound Retention: The polar endcapped C18 phase provides greater retention for polar analytes compared to conventional C18 columns.
  • Excellent Performance with Aqueous Mobile Phases: Designed to operate with 100% aqueous mobile phases, making it suitable for challenging separations.
  • High Separation Efficiency: The 3 µm particle size delivers sharp peaks, high resolution, and reliable analytical performance.
  • Consistent Chromatographic Results: High-quality silica packing ensures reproducible retention times and dependable analytical results.
  • Versatile Laboratory Applications: Suitable for pharmaceutical, biotechnology, food safety, environmental, and research laboratories.
  • LC/MS Compatibility: Optimized for use in both conventional HPLC and LC/MS analytical workflows.
  • Reliable Method Development: Offers alternative selectivity for improved method optimization and difficult compound separations.
  • Long Column Life: Robust silica-based stationary phase provides dependable performance during routine laboratory analysis.

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