The Thermo Scientific™ Acclaim™ Mixed-Mode HILIC-1 HPLC Column (3 µm, 3 × 150 mm) is a high-performance analytical column designed for the separation of both highly polar and non-polar compounds using Hydrophilic Interaction Liquid Chromatography (HILIC) and Reversed-Phase (RP) chromatography. Its unique mixed-mode stationary phase combines a hydrophobic alkyl chain with a terminal diol functional group, providing exceptional selectivity, excellent peak symmetry, and high-resolution separations for a broad range of analytes.
The Acclaim Mixed-Mode HILIC-1 column offers greater flexibility than conventional HILIC columns by operating in both HILIC and reversed-phase modes, making it suitable for pharmaceutical, biotechnology, environmental, food safety, clinical research, and analytical chemistry laboratories. It provides excellent retention of highly polar molecules while maintaining the ability to separate hydrophobic compounds in a single chromatographic platform.
| Parameter | Specification |
|---|---|
| Product Type | Mixed-Mode HPLC Column |
| Brand | Thermo Scientific™ |
| Product Line | Acclaim™ |
| Model | Mixed-Mode HILIC-1 |
| Column Dimensions | 3 × 150 mm |
| Particle Size | 3 µm |
| Pore Size | 120 Å |
| Stationary Phase | Hydrophobic Alkyl Chain with Terminal Diol Group |
| Packing Material | High-Purity Spherical Porous Silica |
| Chromatography Mode | HILIC & Reversed-Phase |
| pH Range | 2.5–7.5 |
| Maximum Pressure | 5800 psi (400 bar) |
| Recommended Flow Rate | 0.4–1.0 mL/min |
| Application | Analytical HPLC |
