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BETASIL C18 5UM 250X4.6MM COLUMN

The Thermo Scientific™ BetaSil™ C18 HPLC Column (5 µm, 250 × 4.6 mm) is a high-performance reversed-phase analytical HPLC column designed for accurate, reproducible, and efficient chromatographic separations. Built on 100 Å high-purity silica with a high bonded-phase coverage, the BetaSil™ C18 column delivers excellent peak shape, high efficiency, and reliable performance for routine and advanced analytical applications.

Designed for pharmaceutical, environmental, food, chemical, biotechnology, and research laboratories, the BetaSil™ C18 column offers excellent retention and separation of a broad range of polar and non-polar compounds. Its 20% carbon loading, 310 m²/g surface area, and endcapped C18 stationary phase help minimize unwanted secondary interactions while improving analyte resolution and reproducibility.

SKU: 70105-254630 Category: Brand:

Specifications

Parameter Specification
Product Type Analytical HPLC Column
Brand Thermo Scientific™
Product Line BetaSil™
Stationary Phase C18
Chromatography Mode Reversed Phase
Column Dimensions 250 × 4.6 mm
Particle Size 5 µm
Pore Size 100 Å
Packing Material High-Purity Silica
Carbon Load 20%
Surface Area 310 m²/g
Endcapped Yes
USP Classification L1
pH Range 2–9
Column Format Analytical Column
Compatible Techniques HPLC, LC-MS

Features

  • Thermo Scientific™ BetaSil™ C18 analytical HPLC column
  • Reversed-phase C18 stationary phase
  • Column dimensions: 250 × 4.6 mm
  • Particle size: 5 µm
  • High-purity 100 Å silica support
  • High bonded-phase coverage
  • Endcapped stationary phase
  • Carbon loading: 20%
  • Surface area: 310 m²/g
  • Analytical column format
  • pH operating range: 2–9
  • Excellent peak symmetry and reproducibility
  • High separation efficiency
  • Suitable for HPLC and LC-MS applications
  • USP L1 equivalent column chemistry
  • Ideal for routine analytical and quality control laboratories

Benefits

  • Excellent Chromatographic Performance: High bonded-phase coverage and endcapping provide sharp peaks, improved resolution, and consistent analytical performance.
  • High Separation Efficiency: The 250 mm column length and 5 µm particle size deliver excellent efficiency for complex sample separations.
  • Reduced Secondary Interactions: Endcapped C18 chemistry minimizes silanol interactions for improved peak symmetry and reproducibility.
  • Wide Application Compatibility: Suitable for pharmaceutical, environmental, food, biotechnology, forensic, and chemical analysis.
  • Reliable Method Reproducibility: High-quality silica packing ensures consistent retention times and dependable analytical results.
  • Broad Chemical Compatibility: The pH operating range of 2–9 supports a variety of mobile phases and analytical methods.
  • LC-MS Compatible: Suitable for modern HPLC and LC-MS analytical workflows.
  • Long Column Lifetime: High-purity silica and durable bonded phase provide reliable long-term performance under recommended operating conditions.

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