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BETASIL C8 5UM 125X4.6MM COLUMN

The Thermo Scientific™ BetaSil™ C8 HPLC Column (5µm, 125 × 4.6 mm) is a high-performance reversed-phase analytical HPLC column designed to deliver excellent separation efficiency, reproducibility, and peak symmetry for a wide range of chromatographic applications. Featuring high surface area silica with high bonded phase coverage, the column offers reliable performance for pharmaceutical, environmental, food, clinical, biotechnology, and research laboratories.

Packed with 5 µm spherical silica particles and a 100 Å pore size, the BetaSil™ C8 column provides outstanding chromatographic performance for moderately hydrophobic compounds. The endcapped octyl (C8) stationary phase minimizes secondary interactions, resulting in improved peak shape, higher reproducibility, and enhanced analytical accuracy.

SKU: 70205-124630 Category: Brand:

Specifications

Parameter Specification
Product Type Analytical HPLC Column
Brand Thermo Scientific™
Product Line BetaSil™
Model BetaSil™ C8
Column Chemistry Octyl (C8)
Chromatography Mode Reversed Phase
Column Dimensions 125 × 4.6 mm
Particle Size 5 µm
Pore Size 100 Å
Packing Material High-Purity Spherical Silica
Particle Shape Spherical
Endcapped Yes
Surface Area 310 m²/g
Carbon Load 12%
Surface Coverage High Bonded Phase Coverage
USP Classification L7
Operating pH Range 2–9
Compatible Techniques HPLC & LC/MS

Features

  • Thermo Scientific™ BetaSil™ C8 analytical HPLC column
  • Column dimensions: 125 × 4.6 mm
  • Particle size: 5 µm
  • Reversed-phase C8 (Octyl) stationary phase
  • High surface area silica packing
  • High bonded phase coverage
  • Endcapped stationary phase for improved peak symmetry
  • 100 Å pore size
  • Spherical silica particles
  • Carbon load of 12%
  • Surface area of 310 m²/g
  • Suitable for HPLC and LC/MS separations
  • Wide operating pH range of 2–9
  • USP Classification L7
  • Excellent reproducibility and column efficiency
  • Suitable for routine analytical applications

Benefits

  • Excellent Separation Performance: High bonded phase coverage provides efficient separation and improved chromatographic resolution.
  • Superior Peak Shape: Endcapped C8 chemistry minimizes unwanted secondary interactions and tailing.
  • Reliable Analytical Results: High-purity spherical silica ensures consistent retention times and reproducible performance.
  • Optimized for LC/MS: Designed for compatibility with HPLC and LC/MS analytical methods.
  • Broad Chemical Compatibility: Operates across a pH range of 2–9, making it suitable for diverse mobile phases and analytes.
  • Reduced Hydrophobic Retention: C8 chemistry provides faster elution than C18 columns, making it suitable for moderately non-polar compounds.
  • Long Column Lifetime: Durable silica packing and high bonded phase coverage contribute to reliable long-term performance.
  • Suitable for Validated Methods: USP L7 classification supports pharmaceutical quality control and regulated laboratory workflows.

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