The Thermo Scientific™ HyPURITY™ ADVANCE HPLC Column (5 µm, 50 × 4.6 mm) is a high-performance reversed-phase C8 analytical column designed for fast, reliable, and reproducible chromatographic separations. Built on HyPURITY™ 190 Å ultra-pure silica with a polar-embedded stationary phase, this column offers superior peak shape and alternate selectivity for compounds that exhibit poor chromatography on conventional C18 columns.
The HyPURITY™ ADVANCE column is particularly suitable for pharmaceutical analysis, bioanalytical testing, environmental monitoring, food safety, chemical analysis, and LC/MS applications. Its polar-embedded chemistry minimizes unwanted interactions with residual silanol groups, providing exceptional peak symmetry for acidic, basic, and chelating compounds while maintaining enhanced stability in highly aqueous mobile phases.