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HYPURITY C18 5UM 250X4.6MM COLUMN

The Thermo Scientific™ HyPURITY™ C18 HPLC Column (5 µm, 250 × 4.6 mm) is a premium reversed-phase analytical HPLC column designed to deliver high-resolution separations, excellent peak symmetry, and outstanding reproducibility for routine and advanced chromatographic applications. Manufactured using high-purity silica with a highly characterized C18 bonded stationary phase, the column offers exceptional performance for pharmaceutical, environmental, food, biotechnology, and research laboratories.

The HyPURITY™ C18 column features a 190 Å pore size, 13% carbon load, and 200 m²/g surface area, providing excellent retention and selectivity for a wide range of polar and non-polar compounds. Its endcapped silica packing minimizes secondary interactions, resulting in improved peak shapes, enhanced sensitivity, and reliable analytical performance.

SKU: 22105-254630 Category: Brand:

Specifications

Parameter Specification
Product Type Analytical HPLC Column
Brand Thermo Scientific™
Product Series HyPURITY™
Stationary Phase C18
Chromatography Type Reversed Phase (RP-HPLC)
USP Classification L1
Column Dimensions 250 × 4.6 mm
Particle Size 5 µm
Pore Size 190 Å
Surface Area 200 m²/g
Carbon Load 13%
Packing Material High-Purity Silica
Endcapped Yes
Operating pH Range 1–9
LC/MS Compatible Yes
Catalog Number 22105-254630

Features

  • Thermo Scientific™ HyPURITY™ C18 analytical HPLC column
  • Column dimensions: 250 × 4.6 mm
  • Particle size: 5 µm
  • Reversed-phase chromatography column
  • High-purity silica stationary phase
  • C18 bonded stationary phase
  • USP L1 classification
  • Endcapped silica packing
  • 190 Å pore size
  • 200 m²/g surface area
  • 13% carbon load
  • Operating pH range: 1–9
  • Excellent peak symmetry and reproducibility
  • High separation efficiency
  • Suitable for LC and LC-MS compatible applications
  • Long column lifetime and robust performance
  • Ideal for routine analytical and research laboratories

Benefits

  • High Separation Efficiency: Delivers excellent chromatographic resolution for complex sample mixtures.
  • Superior Peak Symmetry: Endcapped C18 stationary phase minimizes secondary interactions and improves peak shape.
  • Excellent Reproducibility: Highly characterized silica packing ensures consistent and repeatable analytical results.
  • Broad Compound Compatibility: Suitable for the analysis of pharmaceutical compounds, organic molecules, environmental samples, food products, and biochemical analytes.
  • Extended Column Lifetime: High-purity silica provides excellent chemical stability and long operational durability.
  • Wide pH Compatibility: Operates efficiently across a pH range of 1–9, supporting a variety of analytical methods.
  • Reliable Quality Control: Ideal for pharmaceutical quality control, impurity profiling, assay development, and routine HPLC analysis.
  • LC-MS Compatible: Suitable for modern liquid chromatography systems and compatible analytical workflows.

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