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SYN C8 250X4.6MM 5UM

The Thermo Scientific™ Syncronis™ C8 HPLC Column (250 × 4.6 mm, 5 µm) is a high-performance reversed-phase analytical HPLC column designed to deliver exceptional reproducibility, high efficiency, and reliable chromatographic performance for routine and advanced analytical applications. Packed with high-purity, fully porous ultrapure silica, the column features a C8 stationary phase that offers lower hydrophobicity than traditional C18 columns, making it ideal for compounds requiring moderate retention and faster elution.

Engineered with double end-capping and dense stationary phase coverage, the Syncronis™ C8 column minimizes secondary interactions and improves peak symmetry, particularly for basic compounds. Its 100 Å pore size, 10% carbon loading, and 320 m²/g surface area provide excellent chromatographic efficiency, reproducibility, and batch-to-batch consistency.

SKU: 97205-254630 Category: Brand:

Specifications

Parameter Specification
Product Type Analytical HPLC Column
Brand Thermo Scientific™
Product Line Syncronis™
Stationary Phase C8
Column Dimensions 250 × 4.6 mm
Particle Size 5 µm
Column Type Reversed Phase
Packing Material Spherical, Fully Porous Ultrapure Silica
Pore Size 100 Å
Carbon Load 10%
Surface Area 320 m²/g
End-Capping Double End-Capped
USP Classification L7
pH Range 2–8
Maximum Operating Pressure 400 bar (5800 psi)
Maximum Temperature 60°C

Features

  • Thermo Scientific™ Syncronis™ C8 HPLC Column
  • Analytical reversed-phase HPLC column
  • Column dimensions: 250 × 4.6 mm
  • Particle size: 5 µm
  • C8 stationary phase for moderate hydrophobic retention
  • High-purity fully porous ultrapure silica packing
  • Double end-capped stationary phase
  • Dense phase coverage minimizes secondary interactions
  • 100 Å pore size
  • 10% carbon loading
  • 320 m²/g surface area
  • Highly inert towards basic compounds
  • Excellent batch-to-batch reproducibility
  • High column efficiency and peak symmetry
  • Maximum operating pressure: 400 bar (5800 psi)
  • Recommended operating pH: 2–8
  • Suitable for routine and analytical HPLC applications
  • USP Classification: L7

Benefits

  • Excellent Separation Performance: The Syncronis™ C8 stationary phase provides reliable reversed-phase separations with moderate hydrophobic retention for a wide range of analytes.
  • Improved Peak Shape: Double end-capping minimizes unwanted silanol interactions, producing sharp, symmetrical peaks, especially for basic compounds.
  • High Reproducibility: Manufactured using high-purity silica and stringent quality control to deliver consistent performance from column to column.
  • Faster Elution than C18 Columns: The lower hydrophobicity of the C8 phase reduces retention time, enabling faster analyses without compromising separation quality.
  • High Chromatographic Efficiency: The optimized particle size and high surface area support excellent resolution and analytical sensitivity.
  • Wide Laboratory Compatibility: Suitable for pharmaceutical, environmental, food, chemical, and research laboratories performing routine HPLC analysis.
  • Long Operational Life: Durable stationary phase chemistry provides reliable performance for routine analytical workflows.
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