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SYNCRONIS AQ 250X4.6MM,5UM

The Thermo Scientific™ Syncronis™ aQ C18 HPLC Column (250 × 4.6 mm, 5 µm) is a high-performance reversed-phase analytical HPLC column specifically designed for the reliable separation of polar and moderately polar compounds. Featuring a polar end-capped C18 stationary phase, the column provides excellent retention of polar analytes while maintaining outstanding performance with 100% aqueous mobile phases, making it ideal for challenging chromatographic applications.

Manufactured using high-purity, fully porous spherical silica particles, the Syncronis™ aQ column delivers exceptional peak symmetry, high column efficiency, and reproducible chromatographic results. Its robust design supports routine pharmaceutical analysis, environmental testing, food safety analysis, clinical research, and quality control laboratories.

SKU: 97305-254630 Category: Brand:

Specifications

Parameter Specification
Product Type Analytical HPLC Column
Brand Thermo Scientific™
Product Line Syncronis™
Model aQ C18
Column Dimensions 250 × 4.6 mm
Particle Size 5 µm
Stationary Phase C18
Column Type Reversed Phase
Endcapping Polar End-Capped
Packing Material High-Purity Fully Porous Spherical Silica
Pore Size 100 Å
Carbon Load 19%
Surface Area 320 m²/g
USP Classification L1
Maximum Pressure 400 bar (5800 psi)
Maximum Temperature 60°C
pH Range 2–8
Mobile Phase Compatibility Up to 100% Aqueous
Application Analytical HPLC

Features

  • Thermo Scientific™ Syncronis™ aQ analytical HPLC column
  • Reversed-phase C18 stationary phase
  • Polar end-capped chemistry for enhanced polar compound retention
  • Column dimensions: 250 × 4.6 mm
  • Particle size: 5 µm
  • Compatible with 100% aqueous mobile phases
  • High-purity spherical porous silica packing
  • Excellent peak symmetry and reproducibility
  • High column efficiency and resolution
  • Stable chromatographic performance
  • Suitable for polar and moderately polar analytes
  • Maximum operating pressure: 400 bar (5800 psi)
  • Wide pH operating range: 2–8
  • Pore size: 100 Å
  • Carbon load: 19%
  • Maximum operating temperature: 60°C
  • USP Type L1 column chemistry
  • Designed for routine HPLC analysis and quality control applications

Benefits

  • Excellent Retention of Polar Compounds: The polar end-capped C18 chemistry enhances retention of highly polar analytes that are difficult to separate using conventional C18 columns.
  • Compatible with 100% Aqueous Mobile Phases: Designed to maintain performance and stability in highly aqueous mobile phases without phase collapse.
  • High Separation Efficiency: Optimized silica particles provide sharp peaks, improved resolution, and excellent reproducibility.
  • Reliable Analytical Performance: Delivers consistent retention times and peak symmetry for routine laboratory and quality control applications.
  • Versatile HPLC Applications: Suitable for pharmaceutical, environmental, food, chemical, biotechnology, and clinical laboratory analyses.
  • Robust Column Stability: Wide pH tolerance and durable stationary phase support long column life and dependable operation.
  • Improved Method Development: Offers predictable selectivity for analytical method optimization and validation.
  • Supports Regulatory Compliance: USP L1 chemistry and reproducible performance make it suitable for regulated analytical laboratories.
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